4 ms·

I'll bite.. while we all have unique experiences in life, I believe Sasha and Anne's positive lifetime experiences with psychedelics is neither unusual nor surp

I'll bite.. while we all have unique experiences in life, I believe Sasha and Anne's positive lifetime experiences with psychedelics is neither unusual nor surprising, and not that hard to replicate. 1) It's not that hard to take low doses of psychedelics as regularly or irregularly as you'd like. They are extremely non-compulsive. 2) Testing is not so hard these days in many parts of the world. In my city there are at least a couple mass spectrometry machines available for free testing. Besides that, no need for powders from the internet; growing magic mushrooms at home is a simple project anyone can take on. 3) No we don't have a study, so like a lot of things in life we have to rely on more informal observation and anecdotes. A couple of other notable psychedelic old-timers are Albert Hofmann, Paul Stamets. I've met many "psychedelic seniors" over the years, and they've always been very bright, admirable people. Personally, I've been using psychedelics for 30y, and while I can see that they aren't completely without risks, on the whole they are of great benefit and I plan on aging into becoming one of these psychedelic seniors myself. 4) Psychedelic use is associated with improved mental health outcomes: - https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063972 https://journals.plos.org/plosone/article?id=10.1371/journal... - https://journals.sagepub.com/doi/10.1177/0269881114565653 https://journals.sagepub.com/doi/10.1177/0269881114565653 - https://akjournals.com/view/journals/2054/5/2/article-p83.xml https://akjournals.com/view/journals/2054/5/2/article-p83.xm... I haven't heard of the psychedelic chemist who had a mental breakdown, I think that's a myth. The biggest risk to mental health for a psychedelic chemist is ending up in prison.

elevaet 5y ago
Another study re: psychedelics and mental health: https://www.nature.com/articles/s41386-022-01301-9 https://www.nature.com/articles/s41386-022-01301-9 "Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline" (in mice)
verbify 5y ago
> I haven't heard of the psychedelic chemist who had a mental breakdown, I think that's a myth. The biggest risk to mental health for a psychedelic chemist is ending up in prison. Anecdotally I do know someone who had a psychotic episode on psychedelics and spent awhile in recovery. They eventually did recover, but that did make me wary. As for your point about doses - low doses are hard on chemicals because you don't know what you're getting. Using mushrooms, well dosage varies wildly per gram depending on what you've picked. It wasn't a point about addiction. I have had great experiences on threshold doses of mushrooms (and experimented on much higher doses of acid in my past), but I do think a healthy amount of caution is generally good.
- elevaet 5y ago
  > a healthy amount of caution is generally good. Definitely. These are potent levers, not toys. Knowing your dose is critical and really does need to be emphasized. Thanks. Re: chemicals - you can know very accurately but you really have to know what you're doing and most people aren't up for the effort.

elevaet 5y ago

Another study re: psychedelics and mental health: https://www.nature.com/articles/s41386-022-01301-9 https://www.nature.com/articles/s41386-022-01301-9 "Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline" (in mice)

verbify 5y ago

> I haven't heard of the psychedelic chemist who had a mental breakdown, I think that's a myth. The biggest risk to mental health for a psychedelic chemist is ending up in prison. Anecdotally I do know someone who had a psychotic episode on psychedelics and spent awhile in recovery. They eventually did recover, but that did make me wary. As for your point about doses - low doses are hard on chemicals because you don't know what you're getting. Using mushrooms, well dosage varies wildly per gram depending on what you've picked. It wasn't a point about addiction. I have had great experiences on threshold doses of mushrooms (and experimented on much higher doses of acid in my past), but I do think a healthy amount of caution is generally good.

elevaet 5y ago
> a healthy amount of caution is generally good. Definitely. These are potent levers, not toys. Knowing your dose is critical and really does need to be emphasized. Thanks. Re: chemicals - you can know very accurately but you really have to know what you're doing and most people aren't up for the effort.