Prozac is an antagonist (not agonist) of the 5HT2C receptor at higher doses. At lower doeses the increased serotonin from SERT inhibition will stimulate 5HT2C.

Prozac is an antagonist (not agonist) of the 5HT2C receptor at higher doses. At lower doeses the increased serotonin from SERT inhibition will stimulate 5HT2C. https://www.pnas.org/doi/pdf/10.1073/pnas.94.5.2036 https://www.pnas.org/doi/pdf/10.1073/pnas.94.5.2036