4 ms·
All SSRIs are 5-HT2b agonists, apparently. Do people taking antidepressants have a higher instance of heart disease?
by subpixel 5y ago
All SSRIs are 5-HT2b agonists, apparently. Do people taking antidepressants have a higher instance of heart disease?
- SpodGaju 5y agoProzac is an antagonist (not agonist) of the 5HT2C receptor at higher doses. At lower doeses the increased serotonin from SERT inhibition will stimulate 5HT2C. https://www.pnas.org/doi/pdf/10.1073/pnas.94.5.2036 https://www.pnas.org/doi/pdf/10.1073/pnas.94.5.2036