I'm always amazed by the number of people who use the native Twitter interface. I started with third party clients pretty early and never regretted it. Being

I'm always amazed by the number of people who use the native Twitter interface. I started with third party clients pretty early and never regretted it. Being able to see a natural, unmolested timeline + the advanced filtering tools most third party clients provide make them essential (for me anyway) if you are going to screw with twitter at all.