3 ms·
I don't get why this is called rare in the article. It's not called that in the actual study, so the article seems to do some editorializing: https://www.acpjo
by golem14 5y ago
I don't get why this is called rare in the article. It's not called that in the actual study, so the article seems to do some editorializing:
https://www.acpjournals.org/doi/10.7326/M21-4389 https://www.acpjournals.org/doi/10.7326/M21-4389
Looks like of the kids taken from dads taking metformin, .9% had a genital defect, which seems pretty high to me (defect in control is 0.24%). Granted, not as high as Thalidomide, but still, 9 in 1000 are not great odds.
- pxeger1 5y agoI think it means the genital defect is normally rare, but is much more common in these kids?
- golem14 5y agoEven .24% isn't that rare. From NIH.gov: "In the United States, a rare disease is defined as a condition that affects fewer than 200,000 people in the US."
- ianai 5y agoThat works out to 6.0341E-06%
- eMSF 5y agoA condition which would affect 6e-6%, or 0.000006% of the US population (330M) would affect 20 persons. 200000/330M = 0.0006 = 0.06%.
- ccalloway 5y agoThe deformity in the general population affects 0.24% of male babies, so 0.12% of the population.
- InitialLastName 5y agoGGP is still 4 orders of magnitude off.