4 ms·
"All ten of the treated mice survived infection, compared with only 20 per cent of the untreated mice. [...] The compound has the potential to be used as a broa
by jaynetics 5y ago
"All ten of the treated mice survived infection, compared with only 20 per cent of the untreated mice. [...] The compound has the potential to be used as a broad-spectrum treatment against other viruses which use the same mechanism [...] including influenza viruses such as influenza A, H1N1, and influenza C."
But apparently it is most effective very soon after exposure. From the paper [1]:
"in the K18-hACE2 mouse model, treating with
N-0385 resulted in complete protection against SARS-CoV-2 induced
mortality and significantly protected against weight loss, lung pathology, and viral infection when treatment occurred at the time of, or 12
hours after, infection with the SARS-CoV-2 B.1.617.2"
[1] https://www.nature.com/articles/s41586-022-04661-w https://www.nature.com/articles/s41586-022-04661-w