I believe the rationale here is, sure, you need to trust that the vendor isn't giving you malware, but for most software makers that have existed for longer tha

I believe the rationale here is, sure, you need to trust that the vendor isn't giving you malware, but for most software makers that have existed for longer than a few months, you have a reasonable track record to grant that level of trust. On the other hand, trusting that your data won't be exfiltrated somehow is much harder because of how widespread the practice is. But at least desktop software can, in principle, run without network access. A web app cannot. Beyond that, you can also, in principle, run a desktop app in a sandbox and/or audit it in some way to observe its behavior and assure yourself it isn't malicious, and only then use it on a sensitive host. A web app, in contrast, can't even be guaranteed to serve you the same version of itself from one second to the next, let alone guarantee that any change made to it between requests wasn't malicious. The sandboxing done by the browser is the only protection you have (short of only ever visiting the web at all from a sandboxed host). Then get into applications like basic photo processing and document editing. Sure, it can be done server-side via the web, but the only way for that to be possible is for you to upload all of your photos across the network to the server, along with all the threat models that entails. If the software is running on your host, your data can stay on your host. I'm assuming here that pure Javascript is still not really used for compute-intensive applications and things like doc-to-pdf conversion and photo smoothing accomplished via web apps mostly still relies on server-side processing.