4 ms·

The possibility of getting brain fog from long Covid terrifies me so much that I will probably wear a mask indoors for the rest of my life.

sbinthree 5y ago
It is likely going to be found that long covid can be reversed with acute doses of Vitamin B3. Here's a few links, including a Nature article about it: * https://www.nature.com/articles/s41418-020-0530-3 https://www.nature.com/articles/s41418-020-0530-3 * https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322475/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322475/ * Study: https://www.clinicaltrials.gov/ct2/show/NCT04407390 https://www.clinicaltrials.gov/ct2/show/NCT04407390 * https://www.sciencedirect.com/science/article/pii/S1471490622000254 https://www.sciencedirect.com/science/article/pii/S147149062...
- bagels 5y ago
  First paper was published March 2020, and only discusses B3 in the context of lung damage. Last paper doesn't seem to address cognitive function either.
- cjbgkagh 5y ago
  Long Covid is basically CFS/ME with some extra complications. I wish CFS/ME could be treated so easily, it's not like people are not motivated to try.
jimmygrapes 5y ago
bigDinosaur 5y ago
Have you realised that recovery is often very likely? I had brain fog for three months, and it spontaneously vanished after that. I don't know why people act like all 'long covid' is a death sentence. It's just like the fatigue that can come after certain other infections (e.g. EPV) where the vast majority will recover fine, but it might take quite a while (6 months to a year). Very few end up with actual CFS.
- shigawire 5y ago
  Having a foggy brain for 3 months would mess up my life more than wearing a mask.
  - _yoqn 5y ago
    [flagged]
    - stonogo 5y ago
      Your comment might have been more effective in reply to someone supporting a mask mandate, instead of someone choosing to wear one.
    - pthread_t 5y ago
      > Don't mandate it. How far do we take this? Should we stop forcing people to get the MMR vaccine? Polio vaccine? Hep A?
      - _yoqn 5y ago
        The mRNA vaccine is not your grandpa's vaccine. This is a new and experimental technology that is not even close to being fully understood. And there is no data on very long term adverse events. The trial data will not be released by the FDA for another 55 years or so [1] The J&J Janssen vaccine is a more traditional vaccine and it's not pushed by the media or the governments almost at all. [1] https://www.reuters.com/legal/government/wait-what-fda-wants-55-years-process-foia-request-over-vaccine-data-2021-11-18 https://www.reuters.com/legal/government/wait-what-fda-wants...
        internet_user 5y ago
        J&J is a viral vector vaccine and it's also a very new tech. Only 6 are approved. 4 for covid, 2 for ebola. It's just a crappy vaccine, that's why it's not being pushed hard. The inactivated vaccine, which is the actual well established old tech, seems to have worked just as well, or just as poorly, depending on how you percieve the vaccine efficacy. India used mostly the inactivated vaccine, where nearly a billion people have been vaccinated with it. Apparently, that's just not good enough for several western countries that demand you MUST get an mRNA shot, despite being fully vaccinated by inactivated vaccines that were accepted as effective by the WHO. Clearly purely scientific decisions. /s It gets even better. Licensed Astrazeneca vaccine that was made in India is not accepted by the EU, only the UK version that's sold under a different label. duh, this is obviously The Science. /s Most of pharma in the world is manufactured in India, btw. Usually good enough, but for some reason not in a critical emergency such as a pandemic. Why is that?
samatman 5y ago
MikeTheRocker 5y ago
Does anyone have authoritative data indicating how common long-covid is? Anecdotally, I was triple vaccinated (2x Moderna + booster), but I still caught covid twice (Aug 2021 and Jan 2022). Both times I had mild brain fog and cold-like symptoms (runny nose and light headache). Both times I recovered completely within 4 or 5 days. I'm a healthy 25 year-old man living in San Francisco, California. Not trying to imply anything about long-covid, but it hasn't been my experience or that of anyone I personally know.
- cjbgkagh 5y ago
  As a ballpark 10-20% would be expected given other harsh viruses cause CFS/ME 10-20% of the time and Covid is a particularly harsh virus. Not as harsh as MERS though.
nscalf 5y ago
Agreed. I've seen some theories that long covid is related to micro blood clots, and some very preliminary studies showing universal improvements from long term anti-coagulants---though I am far from being an expert able to really vet these papers. I know many people slowly get better as well. Anecdotally, my experience was a relatively large step down in cardio, which I have seen slowly improve, however I'm young and relatively healthy.
- hackernewds 5y ago
  Are you suggesting that long COVID is related to decrease in cardio, or that your cardio decrease led to the effects of long COVID?
  - nscalf 5y ago
    I’m suggesting that my covid led to long covid, which has been characterized as a persistent decrease in cardio capacity. In particular, the worst of it was me gasping for breath after a flight of stairs for about the first month.
- lazide 5y ago
  Long term anticoagulants will have some nasty side effects.
  - nscalf 5y ago
    100%, this is a doctor supervision and recommendation thing. I dug up the researcher talking about it on Twitter (links to pre publish study) https://twitter.com/resiapretorius/status/1476164312318238722?s=20&t=5FPJUuLKwvwjbSgFHWu3Uw https://twitter.com/resiapretorius/status/147616431231823872...
    - lazide 5y ago
      Thanks! And yeah, based on my experiences helping several relatives on anti-coagulant therapy for other reasons (heart problems, clotting), it's really terrible to be on and quite dangerous day to day. Maybe not applicable to someone younger, but the them they literally could never stop either once they started.

sbinthree 5y ago

It is likely going to be found that long covid can be reversed with acute doses of Vitamin B3. Here's a few links, including a Nature article about it: * https://www.nature.com/articles/s41418-020-0530-3 https://www.nature.com/articles/s41418-020-0530-3 * https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322475/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322475/ * Study: https://www.clinicaltrials.gov/ct2/show/NCT04407390 https://www.clinicaltrials.gov/ct2/show/NCT04407390 * https://www.sciencedirect.com/science/article/pii/S1471490622000254 https://www.sciencedirect.com/science/article/pii/S147149062...

bagels 5y ago
First paper was published March 2020, and only discusses B3 in the context of lung damage. Last paper doesn't seem to address cognitive function either.
cjbgkagh 5y ago
Long Covid is basically CFS/ME with some extra complications. I wish CFS/ME could be treated so easily, it's not like people are not motivated to try.

jimmygrapes 5y ago

bigDinosaur 5y ago

Have you realised that recovery is often very likely? I had brain fog for three months, and it spontaneously vanished after that. I don't know why people act like all 'long covid' is a death sentence. It's just like the fatigue that can come after certain other infections (e.g. EPV) where the vast majority will recover fine, but it might take quite a while (6 months to a year). Very few end up with actual CFS.

shigawire 5y ago
Having a foggy brain for 3 months would mess up my life more than wearing a mask.
- _yoqn 5y ago
  [flagged]
  - stonogo 5y ago
    Your comment might have been more effective in reply to someone supporting a mask mandate, instead of someone choosing to wear one.
  - pthread_t 5y ago
    > Don't mandate it. How far do we take this? Should we stop forcing people to get the MMR vaccine? Polio vaccine? Hep A?
    - _yoqn 5y ago
      The mRNA vaccine is not your grandpa's vaccine. This is a new and experimental technology that is not even close to being fully understood. And there is no data on very long term adverse events. The trial data will not be released by the FDA for another 55 years or so [1] The J&J Janssen vaccine is a more traditional vaccine and it's not pushed by the media or the governments almost at all. [1] https://www.reuters.com/legal/government/wait-what-fda-wants-55-years-process-foia-request-over-vaccine-data-2021-11-18 https://www.reuters.com/legal/government/wait-what-fda-wants...
      - internet_user 5y ago
        J&J is a viral vector vaccine and it's also a very new tech. Only 6 are approved. 4 for covid, 2 for ebola. It's just a crappy vaccine, that's why it's not being pushed hard. The inactivated vaccine, which is the actual well established old tech, seems to have worked just as well, or just as poorly, depending on how you percieve the vaccine efficacy. India used mostly the inactivated vaccine, where nearly a billion people have been vaccinated with it. Apparently, that's just not good enough for several western countries that demand you MUST get an mRNA shot, despite being fully vaccinated by inactivated vaccines that were accepted as effective by the WHO. Clearly purely scientific decisions. /s It gets even better. Licensed Astrazeneca vaccine that was made in India is not accepted by the EU, only the UK version that's sold under a different label. duh, this is obviously The Science. /s Most of pharma in the world is manufactured in India, btw. Usually good enough, but for some reason not in a critical emergency such as a pandemic. Why is that?

samatman 5y ago

MikeTheRocker 5y ago

Does anyone have authoritative data indicating how common long-covid is? Anecdotally, I was triple vaccinated (2x Moderna + booster), but I still caught covid twice (Aug 2021 and Jan 2022). Both times I had mild brain fog and cold-like symptoms (runny nose and light headache). Both times I recovered completely within 4 or 5 days. I'm a healthy 25 year-old man living in San Francisco, California. Not trying to imply anything about long-covid, but it hasn't been my experience or that of anyone I personally know.

cjbgkagh 5y ago
As a ballpark 10-20% would be expected given other harsh viruses cause CFS/ME 10-20% of the time and Covid is a particularly harsh virus. Not as harsh as MERS though.

nscalf 5y ago

Agreed. I've seen some theories that long covid is related to micro blood clots, and some very preliminary studies showing universal improvements from long term anti-coagulants---though I am far from being an expert able to really vet these papers. I know many people slowly get better as well. Anecdotally, my experience was a relatively large step down in cardio, which I have seen slowly improve, however I'm young and relatively healthy.

hackernewds 5y ago
Are you suggesting that long COVID is related to decrease in cardio, or that your cardio decrease led to the effects of long COVID?
- nscalf 5y ago
  I’m suggesting that my covid led to long covid, which has been characterized as a persistent decrease in cardio capacity. In particular, the worst of it was me gasping for breath after a flight of stairs for about the first month.
lazide 5y ago
Long term anticoagulants will have some nasty side effects.
- nscalf 5y ago
  100%, this is a doctor supervision and recommendation thing. I dug up the researcher talking about it on Twitter (links to pre publish study) https://twitter.com/resiapretorius/status/1476164312318238722?s=20&t=5FPJUuLKwvwjbSgFHWu3Uw https://twitter.com/resiapretorius/status/147616431231823872...
  - lazide 5y ago
    Thanks! And yeah, based on my experiences helping several relatives on anti-coagulant therapy for other reasons (heart problems, clotting), it's really terrible to be on and quite dangerous day to day. Maybe not applicable to someone younger, but the them they literally could never stop either once they started.