There's a bunch of 386s on the ISS. The main systems on the ISS are MDMs (multiplexer-demutiplexer) that communicate with "dumb" devices like sensors, actuators

There's a bunch of 386s on the ISS. The main systems on the ISS are MDMs (multiplexer-demutiplexer) that communicate with "dumb" devices like sensors, actuators, and motors. The MDMs contain removable boards with a hardened 386, RAM, an EEPROM, and talk over a 1553 bus. Some MDMs live on the outside components of the station and some live inside. Astronauts can replace the CPU boards inside the MDMs if they burn out. The station has a few dozen MDMs each with four or more boards inside.