I think it can somewhat work with flexible timelines. A full 2/5 days a week in-office hybrid is decidedly the worst of both, but a "we come into the office eve

I think it can somewhat work with flexible timelines. A full 2/5 days a week in-office hybrid is decidedly the worst of both, but a "we come into the office every N weeks for 1-2 days to handle major meetings in person" feels both more fair and less disruptive to all parties. Expand it further where folks living further away are maybe only expected to come in quarterly for maybe a full week. It helps to keep up some in-person social constructs - you can spend time with coworkers at lunch, or going out for a group activity if you want, but keeps the majority of the day-to-day focused on making remote work for everyone.