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Yes is it a feature not a bug? "Nickel is a mineral. It is found in several foods including nuts, dried beans and peas, soybeans, grains, and chocolate. The bo

Yes is it a feature not a bug? "Nickel is a mineral. It is found in several foods including nuts, dried beans and peas, soybeans, grains, and chocolate. The body needs nickel, but in very small amounts. Nickel is a common trace element in multiple vitamins." [1] [1] https://www.webmd.com/vitamins/ai/ingredientmono-1223/nickel https://www.webmd.com/vitamins/ai/ingredientmono-1223/nickel

convolvatron 5y ago
chromium isn't so benign, is it?
- s0rce 5y ago
  From the paper: Low levels of Cr (III) are essential for human health and metabolism of glucose, protein, and fat; however adverse effects of oral Cr exposures, such as dermatitis, are also known Cr (VI) is the bad cancer causing version.
- 0xbadcafebee 5y ago
  not if its extensions have malware
HarryHirsch 5y ago
It is a feature, nickel is a cofactor in certain enzymes, and in industrial nations the main source for humans is their stainless steel cookware. On chromium being an essential trace element the jury is still out.
- margalabargala 5y ago
  You have the two swapped. Chromium is the important trace element, nickel is not known if it's needed.
  - HarryHirsch 5y ago
    Sorry, but that is not correct. Urease is the best-known nickel enzyme (yes, I know, it's bacterial), but there are many more, also in eukaryotes: https://onlinelibrary.wiley.com/doi/full/10.1002/pro.3836 https://onlinelibrary.wiley.com/doi/full/10.1002/pro.3836 I don't think anyone has discovered a Cr-containing enzyme but there are hints that it is involved in glucose metabolism.
    - margalabargala 5y ago
      You're being misleading here. Your original comment heavily implied that nickel is essential for humans and stainless steel pans were an important source. Per your source, nickel-containing enzymes are present in "primitive eukaryotes". Not humans. There are no known human enzymes or cofactors that depend on nickel. Chromium, meanwhile, has been known to be an essential trace element in humans for many decades[0][1]. [0] https://pubmed.ncbi.nlm.nih.gov/2602941/ https://pubmed.ncbi.nlm.nih.gov/2602941/ [1] https://pdfs.semanticscholar.org/24a7/c6a0d26945a6063bdcd3f61503c900b64559.pdf https://pdfs.semanticscholar.org/24a7/c6a0d26945a6063bdcd3f6...
yumraj 5y ago
Well, that is counter to what the above paper says: Though Ni is known to be essential to the health of some species, it has not been proven to be essential to the health of humans (3). There are no known human enzymes or cofactors dependent on Ni for normal function

convolvatron 5y ago

chromium isn't so benign, is it?

s0rce 5y ago
From the paper: Low levels of Cr (III) are essential for human health and metabolism of glucose, protein, and fat; however adverse effects of oral Cr exposures, such as dermatitis, are also known Cr (VI) is the bad cancer causing version.
0xbadcafebee 5y ago
not if its extensions have malware

HarryHirsch 5y ago

It is a feature, nickel is a cofactor in certain enzymes, and in industrial nations the main source for humans is their stainless steel cookware. On chromium being an essential trace element the jury is still out.

margalabargala 5y ago
You have the two swapped. Chromium is the important trace element, nickel is not known if it's needed.
- HarryHirsch 5y ago
  Sorry, but that is not correct. Urease is the best-known nickel enzyme (yes, I know, it's bacterial), but there are many more, also in eukaryotes: https://onlinelibrary.wiley.com/doi/full/10.1002/pro.3836 https://onlinelibrary.wiley.com/doi/full/10.1002/pro.3836 I don't think anyone has discovered a Cr-containing enzyme but there are hints that it is involved in glucose metabolism.
  - margalabargala 5y ago
    You're being misleading here. Your original comment heavily implied that nickel is essential for humans and stainless steel pans were an important source. Per your source, nickel-containing enzymes are present in "primitive eukaryotes". Not humans. There are no known human enzymes or cofactors that depend on nickel. Chromium, meanwhile, has been known to be an essential trace element in humans for many decades[0][1]. [0] https://pubmed.ncbi.nlm.nih.gov/2602941/ https://pubmed.ncbi.nlm.nih.gov/2602941/ [1] https://pdfs.semanticscholar.org/24a7/c6a0d26945a6063bdcd3f61503c900b64559.pdf https://pdfs.semanticscholar.org/24a7/c6a0d26945a6063bdcd3f6...

yumraj 5y ago

Well, that is counter to what the above paper says: Though Ni is known to be essential to the health of some species, it has not been proven to be essential to the health of humans (3). There are no known human enzymes or cofactors dependent on Ni for normal function