The irony here is that in order to do any of the above things and to do them to the extent that you have a large impact on the world you have to sacrifice many,

The irony here is that in order to do any of the above things and to do them to the extent that you have a large impact on the world you have to sacrifice many, many other things in your life. You can't be a dedicated parent and slave away 80+ hours/week in a lab doing research. The day has 24 hours for everybody and you can't be world class with a 9-5pm.