> When someone stops being able to tell the difference between fantasy and reality, they join people suffering from psychosis in being vulnerable to delusions a

> When someone stops being able to tell the difference between fantasy and reality, they join people suffering from psychosis in being vulnerable to delusions and hallucinations. Sometimes, sure. But how do you explain differing opinions perceived as facts (ask some people, they'll tell you!), or the common scenario whereby people speak as if they can read minds or the future (pop into any culture war thread right here on HN)? If one has these symptoms while in (or after) a drug-altered state of consciousness is this psychosis, but if one has them under normal consciousness is it not? > It's often said that psychedelics mimic schizophrenia. I think we should not overstretch that analogy, but the attitude of some that artificial 5-HT2A agonism somehow grants your brain access to some deeper fantastical truth is worrying. Do you believe that it does not grant your brain access to some deeper fantastical truth, at all? Do you believe that this belief is true?