> If there was value in permanently pushing it all the way, would the body have evolved to leave it at baseline? Sure. Evolution is not a designer. I'm no bio

> If there was value in permanently pushing it all the way, would the body have evolved to leave it at baseline? Sure. Evolution is not a designer. I'm no biologist, but I think it's pretty clear that evolution gets stuck in local optima all the time. See the common gripe about humans using the same pipe for breathing and eating. That said, I agree that messing with human biology is risky business for uncertain payoff. We simultaneously know mountains and nothing about ourselves and how we function.