4 ms·
We really need nasal vaccines for boosters since those would confer mucosal immunity - first line defenses are in the mucosa.
by UncleOxidant 5y ago
We really need nasal vaccines for boosters since those would confer mucosal immunity - first line defenses are in the mucosa.
- netizen-936824 5y agoCan you cite any sources on differences in tissue response from route of administration?
- UncleOxidant 5y agohttps://www.nytimes.com/2022/02/02/health/covid-vaccine-nasal.html https://www.nytimes.com/2022/02/02/health/covid-vaccine-nasa...
- netizen-936824 5y agoArchive didn't like that link and it's paywalled Got any scholarly sources about this topic?
- officialjunk 5y agohttps://pubmed.ncbi.nlm.nih.gov/33329607/ https://pubmed.ncbi.nlm.nih.gov/33329607/ https://www.nature.com/articles/s41467-021-27063-4 https://www.nature.com/articles/s41467-021-27063-4 https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00582-X/fulltext https://www.thelancet.com/journals/ebiom/article/PIIS2352-39...
- officialjunk 5y agoyes! some nasal/inhaled vaccines are in trials in other countries, but i am not aware of such progress in the US. it will really help PREVENT infections and not just reduce the severity of symptoms.
- curmudgeon22 5y agoIt's not a vaccine, but there are existing nasal sprays [0] with iota-carrageenan, which has anti-viral properties and has been shown in-vitro [1] to be effective against covid: [0] https://www.betadine.ca/nasal-spray/ https://www.betadine.ca/nasal-spray/ [1] https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0237480 https://journals.plos.org/plosone/article?id=10.1371/journal...