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> In what population does polio spread, the unnvacinnated or the vaccinated? In what population are you exposed to it? This is all so weird. An explanation of
by mlyle 5y ago
> In what population does polio spread, the unnvacinnated or the vaccinated? In what population are you exposed to it?
This is all so weird. An explanation of how I understand it:
Polio definitely spreads in the unvaccinated.
If you've given the IPV vaccine, you can later be infected and spread polio (with a little less likelihood), but won't become sick.
If you're given the OPV vaccine, you eventually will have sterilizing immunity, and won't spread it, once immunity develops a small time after vaccination. But the OPV vaccine itself very rarely causes polio outbreaks.
So the recommendations are complicated. If you're in a part of the world without polio spread, you should be given the IPV vaccine.
If you're in a part of the world with endemic polio and a good health system, you should be given the IPV vaccine and then the OPV vaccine a few months later.
If you're in a part of the world with endemic polio and a lacking health system, the best bet is just giving you the OPV vaccine.
- selimthegrim 5y agoWeren't there vaccine derived polio cases from the OPV in Pakistan?
- mlyle 5y ago> If you're given the OPV vaccine, you eventually will have sterilizing immunity, and won't spread it, once immunity develops a small time after vaccination. But the OPV vaccine itself very rarely causes polio outbreaks.
- selimthegrim 5y agoApparently some old P2 vaccine was kept around after it was supposed to be disposed of nationwide and inadvertently administered.
- kelnos 5y agoPerhaps -- the parent explicitly points out that this is a possibility.
- klipt 5y ago> If you've given the IPV vaccine, you can later be infected and spread polio (with a little less likelihood), but won't become sick. > If you're given the OPV vaccine, you eventually will have sterilizing immunity, and won't spread it, once immunity develops a small time after vaccination. But the OPV vaccine itself very rarely causes polio outbreaks. What if we have IPV first then OPV as a booster, would that give sterilizing immunity with less risk?
- mlyle 5y ago> > If you're in a part of the world with endemic polio and a good health system, you should be given the IPV vaccine and then the OPV vaccine a few months later.