2 ms·
You’re right, antibodies are able to recognize shape. Several early steps of the immune response, however, are independent of conformation. For example, in orde
by flobosg 5y ago
You’re right, antibodies are able to recognize shape. Several early steps of the immune response, however, are independent of conformation. For example, in order to be presented, protein antigens are usually processed and chopped into small peptides, and these may be similar between both prion variants. Additionally, prion proteins can be resistant to that sort of processing.
- epgui 5y agoFor more info about what this commenter is talking about: - https://en.wikipedia.org/wiki/Antigen-presenting_cell https://en.wikipedia.org/wiki/Antigen-presenting_cell - https://en.wikipedia.org/wiki/Major_histocompatibility_complex https://en.wikipedia.org/wiki/Major_histocompatibility_compl...