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> they would only have half of the genetic concern I do. It is complicated. If it is due to a flaw in one of the X or Y chromosomes, that greatly changes the c
by tasty_freeze 5y ago
> they would only have half of the genetic concern I do.
It is complicated. If it is due to a flaw in one of the X or Y chromosomes, that greatly changes the calculation. Dominant/recessive categories changes the math.
But ignoring all that, it seems like you have the same risk as your parents: for them, there is a 50% chance they got it from one known carrier; for you, there is a 25% change of having gotten it from each of two known carriers.
- callesgg 5y agoThat is assuming a very simple genetic model that is only fully valid in cases where a symptom is caused by a single gene malfunctioning by it self. Also ignoring gene to gene interactions that can have adative or worse effects.
- tasty_freeze 5y agoExactly -- like I said, it is complicated. What I said was the simplest case possible: not X/Y related, disease caused by a single gene.