4 ms·
The title was taken from the abstract and then I removed words until it fit. DNA was substituted for a couple words and was the next to last change I made as it
by hajile 5y ago
The title was taken from the abstract and then I removed words until it fit. DNA was substituted for a couple words and was the next to last change I made as it does alter the meaning slightly (though probably not meaningfully for most people).
The question here isn’t stability. The mRNA was present in the cDNA sometime within 6 hours. That isn’t some fluke, but instead points to something that happens somewhat readily.
The fact that clinical side effects seem related means we need to be replicating toes study and if that is consistent we need to start testing in other cells.
Finally, we should be on the lookout for any cancers seeing large increases in diagnosis after late December 2020
- jimrandomh 5y ago"Human liver" vs "human liver cell line" may sound like only a slight alteration in meaning to a layperson, but it's actually an enormous difference. I don't think anyone is particularly surprised to hear that a cancer cell line is expressing reverse transcriptase and grabbing random mRNA. People would be very surprised to hear that about cells in a random human.
- hajile 5y agoThat's true, but what other word would I drop to add those words? Maybe it's too much to assume people on a technical forum will read the paper (or at least the abstract/conclusion) for themselves.