4 ms·
You still need a control group and blinding, as there are a number of ways errors can creep in to studies like this.
by cpncrunch 5y ago
You still need a control group and blinding, as there are a number of ways errors can creep in to studies like this.
- PragmaticPulp 5y agoIt doesn’t need a control group any more than a cancer study requires a control group before it can determine whether or not the cancer patients have cancer.
- cpncrunch 5y agoIt's not quite like cancer. They count antibody staining under a microscope, so there are multiple ways that can go wrong. You have a control group to see what % of your control group shows up positive. Take for example the criteria for POTS: a 30bpm rise on standing. Well, research shows that 80% of control subjects have 30+ bpm rise on standing. I have a 40-50bpm rise on standing, even though I'm incredibly healthy and fit. The article doesn't mention what criteria it used for autonomic function testing, so I'm not saying they used this test. It's just an example of why you need control groups. This isn't cancer...you don't just do an xray and see a big lump!