3 ms·
"Heroin" in the US is essentially almost entirely fentanyl analogues these days. The only safe way to dose fentanyl analogues is volumetric - which is not how t
by atdrummond 5y ago
"Heroin" in the US is essentially almost entirely fentanyl analogues these days. The only safe way to dose fentanyl analogues is volumetric - which is not how the vast majority of drug users use opiods (or really any drugs). Otherwise, fentanyl is extremely likely over continued use to result in a user using more than intended. This, combined with polydrug use complications, has been driving the increased opiod death rate.
Legal drugs could ensure users are getting what they actually want. See: DULF providing chemically pure diacetylmorphine, cocaine, methamphetamine in Vancouver.
- xyzzy21 5y agoNo it's not. Heroin has only modest blood-brain penetration. Fentanyl has nearly 100% penetration. This difference is what makes fentanyl so much stronger than heroin and so much more dangerous. Biochemically it's a different thing - not "just another opiate".
- atdrummond 5y agoHuh? What comment are you referring to? I didn't call fentanyl and similar analogues "just another opiate". (Also, fentanyl is an opiod. It is not a natural opiate. And diacetylmorphine, thanks to its improved lipid solubility compared to morphine, has an approximately 70% brain absorption rate. That's not "modest".) Your reply really confuses me.