CRISPR is the generic name for a system of proteins and RNA found in bacteria. It was discovered by Francisco Mojica. They all chomp viruses' DNA. Different ba

CRISPR is the generic name for a system of proteins and RNA found in bacteria. It was discovered by Francisco Mojica. They all chomp viruses' DNA. Different bacteria have different proteins. Among these proteins the most interesting is the CAS-9, isolated "in vitro" by the teams of Jennifer Doudna and Emanuele Charpentier. They also showed it could be programmed to handle different DNA sequences. Feng Zhang then proceeded to do the same in vivo, with eukaryotes, months after. Doudna and Charpentier filed the application first but the Broad Institute filed it with a express requirement so they were granted first.