I think a passive house design would be excellent for you. Highly insulated, air tight (but vapor permeable) building envelope. Constant intake of fresh air to

I think a passive house design would be excellent for you. Highly insulated, air tight (but vapor permeable) building envelope. Constant intake of fresh air to bedrooms living rooms, filtered and passed through a heat exchanger to heat or cool it with air exhausted from kitchen and bathrooms. They generally cost about ~25% more than a standard code-built house (unless you want a lot of windows), but cost much less to heat and cool. They're also more comfortable and have less pollen, dust, and even insects.