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this was done in vitro with carcinomal cells; not in vivo whole organism. Vaccines Are Not Injected Into Your Liver! vaccines dont travel from innoculation si
by rolph 5y ago
this was done in vitro with carcinomal cells; not in vivo whole organism.
Vaccines Are Not Injected Into Your Liver!
vaccines dont travel from innoculation site to your liver, the products of the immune regime incurred will travel to the liver via lymphatic system and sent to the intestinal tract to be eliminated/defaecated.
any cell expressing the vaccine antigen protien on its surface will be treated as a pathogenic antigen and destroyed in the same way as muscles cells in the shoulder and contribute to the overall immune response.
Early on in biotech there was an effort to determine what conditions led to transfection and incorporation, of extragenomic nucleic acids, this occured at a low rate by manipulationg the extracellular tonicity and ionic species along with addition of NA roughly 1 successful transfection event per thousand cells was considered to be the expected average
- opensores 5y agoThe next step of course is to see if this can also be observed in other human cell cultures. Or if the fundamental mechanism is understood from this, one could make a good guess of whether or not (or to what extent) it does.
- rolph 5y agothis can be observed in a wide range of cell cultures, human and beyond. that has been worked with for about 25 years. the problem in the context of genetic engineering is to achieve predictable, directed transfection and incorporation, in an expressible and regulated form.