9 ms·
> do you understand that there is no one "the sequence"? The linked paper is, literally, about a specific sequence. That’s the paper we’re discussing in this
by PragmaticPulp 5y ago
> do you understand that there is no one "the sequence"?
The linked paper is, literally, about a specific sequence. That’s the paper we’re discussing in this comment section.
- dnautics 5y agoI'm sorry, that is simply not the case, neither at the protein level nor at the DNA level. Furin cleavage sites have diversity. The canonical minimal furin cleavage site sequence is RX(R/K)R, which had a highly variable amino acid and a choice between the two basic amino acids in another position. This variability is sampled across the coronavirus furin cleavage site sequences.