I find it actually the other way around. As you said, a benefit of large distributed systems is that usually its a shared responsibility, with different teams

I find it actually the other way around. As you said, a benefit of large distributed systems is that usually its a shared responsibility, with different teams owning different services. The exhaustion comes into place when those services are not really independent, or when the responsibility is not really shared, which in turn is just a worse version of a typical system maintained by sysadmins. One thing that helps is bring the DevOps culture into the company, but the right way. It's not just about "oh cool we are now agile and deploy a few times a day", it's all down to shared responsibility.