3 ms·
The study says they were given treatment "within 7 days" of onset. The proponents of IVM have always said "early treatment" was required for it to work. Seriou
by nu11ptr 5y ago
The study says they were given treatment "within 7 days" of onset. The proponents of IVM have always said "early treatment" was required for it to work.
Serious question: Does "within 7 days" meet the definition of "early treatment"? My guess would be "no", but curious what others think.
NOTE: To be clear, I have no opinion here. Just like discussion and curious on thoughts.
- dundarious 5y agoIn the vast majority of the anecdotes I know where the person developed serious symptoms, they first had quite mild symptoms for about a week or two, sometimes longer. Given how many people develop no serious symptoms at all, I think "within 7 days" is ambiguously but defensibly in the "early" category.
- s1artibartfast 5y agoIt is still a relevant point given recently approved medications like Paxlovid ran their trials with a even tighter window of <5 days and 50% of the trail was <3 days.
- s1artibartfast 5y ago>In the vast majority of the anecdotes I know where the person developed serious symptoms, they first had quite mild symptoms for about a week or two, sometimes longer. Serious symptoms arent usually caused by the virus, which peaks 3-5 days after symtoms, then dies out. If you want to treat in the viral stage, early action is incredibly important. If you want to treat the after effects, it is less critical.