In short, severe hypoglycemia is an immediate risk to your life, and prolonged hypos <50mg/dL can lead to brain damage, especially in infants or people who don'

In short, severe hypoglycemia is an immediate risk to your life, and prolonged hypos <50mg/dL can lead to brain damage, especially in infants or people who don't have a lot of reserves. Gluconeogenesis still happens, but an insulin overdose can tank your blood sugar much faster than your liver can keep up.