One of the big issues with this approach is that you have to effectively kill the person's immune system with very high dose chemo before introducing the resist

One of the big issues with this approach is that you have to effectively kill the person's immune system with very high dose chemo before introducing the resistant bone marrow cells. While BM transplantation is routinely performed, there are instances where the transplant is not successful (for reasons other than HLA match, etc), with the failure of bone marrow engraftment being typically fatal. Given this, and that the current anti-retroviral drugs generally work pretty well (i.e. those taking the medication enjoy a reduced risk of mortality), this curative treatment might not be pursued.