I think it's enough for them to say to those who have already been vaccinated with mRNA-1273 that there's essentially a "vendor lock-in" effect going on and th

I think it's enough for them to say to those who have already been vaccinated with mRNA-1273 that there's essentially a "vendor lock-in" effect going on and that using an Omicron (or whatever variant comes next) specific booster won't provide any more benefit (for better or worse) than simply getting another dose of the same vaccine they already had. I would be interested to know what would happen in the case where subjects have natural immunity then get mRNA-1273 then later get mRNA-1273.529. I would hypothesize that there would be a measurably different immune response to both the initial vaccine doses as well as the booster.