3 ms·
Exercise also helps clear lymph from most of the body which seems to help the brain clear it while sleeping, at least anecdotally. See also this comment: https
by DoreenMichele 5y ago
Exercise also helps clear lymph from most of the body which seems to help the brain clear it while sleeping, at least anecdotally. See also this comment:
https://news.ycombinator.com/item?id=25427090 https://news.ycombinator.com/item?id=25427090
- ck2 5y agoThe reason why exercise does things that diet alone cannot is likely AMPK activation. AMPK is the "garbage collection" for the body/mind. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779044/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779044/
- leksak 5y agoI think you'd have to be more specific than "exercise" as heavy resistance training activates mTor and not AMPK. If memory serves they are mutually exclusive and cannot be activated simultaneously. Low intensity exercise, such as walking and easy running stimulates AMPK - as does extended fasting.
- ck2 5y agoSome really smart researcher applied clinical trial data to make a calculator to guesstimate what different intensities and durations of exercise will activate AMPK to various levels: https://rothschild.shinyapps.io/AMPK_dashboard/ https://rothschild.shinyapps.io/AMPK_dashboard/ Fun to play with.
- somebodythere 5y agoHow long is extended?
- inglor_cz 5y agoDuring covid, my 70 y.o. mom started going on long walks (like five miles) and fasting. Mostly out of boredom, she self-isolated. I noticed that she is a lot sharper now. Previously, she would forget something in a conversation or ask twice. Now she is absolutely here and if we for example discuss some video, she mentions details that I overlooked. That was quite a change.