6 ms·

Somewhat related I always find the statistic amazing that like 90% of people have EBV (mono) and VZW (herpes, chicken pox, shingles) dormant just waiting for ac

by ck2 5y ago

Somewhat related I always find the statistic amazing that like 90% of people have EBV (mono) and VZW (herpes, chicken pox, shingles) dormant just waiting for activation. Now HIV rising up and of course covid will be with us forever as impossible to irradiate once going back and forth between the animal/human population. At some point science is going to have to find a way to hunt down viruses in our systems, hiding in immune privileged sites where antibodies cannot get to them. HIV shows how near impossible that task is right now with current knowledge/technology.

okokwhatever 5y ago
Life and dead happens and whatever we try to fix about it will be a pursue of decades/centuries to achive. We're simply more aware about our humanity this days and we're more awaken about how simple is to suffer a terminal illness just "existing" not only smoking, eating fat or living an unhealthy life. I hope everyone learns about how life and dead works for the human being and not just trying to forget it submerging in an unreal dystopy of pills and pilates classes.
- mrkramer 5y ago
  >Life and dead happens Life is like Schrödinger's cat; you can be alive or dead at any moment it's all probability.
- pengaru 5y ago
  > smoking, eating fat or living an unhealthy life Eating fat is not unhealthy.
  - nix23 5y ago
    >Eating fat is not unhealthy. True, let's correct it...sugar.
- luckman212 5y ago
  Interested to hear more about those dystopian pilates classes. And to think, I was shelling out my hard-earned money when I could have just been popping pills for the same effect.
pessimizer 5y ago
> Now HIV rising up "for decades"
mistrial9 5y ago
> 90% of people no, that varies by communities of people, defined by a graph of their location, hygiene and intimate practices. I can say that a different percentage probability applies to the graph of Orthodox Hasidim in Brooklyn versus the graph of professional basketball players in the USA.
- cjbgkagh 5y ago
  I always thought negatives was people who either haven’t had sex yet or haven’t had sex outside a closed loop. I’d be interested to see percentage effected normalized by number of partners. (Not interested enough to look it up now though)
  - vsef 5y ago
    The viruses listed by parent aren't spread sexually, though they are all herpes viruses. EBV is also known as HSV-4 and gets to 60% plus prevalence in children, 90% in US adults. If there are populations with especially low prevalence I'm not aware of it. HSV-1 which causes mouth cold sores is present in 50-80% of people, also easily acquired in childhood. Only 20-40% of infected people get cold sores so most infected people don't realize they have it. Chicken pox/shingles is also a type of herpes virus with well known massive prevalence! Genital herpes is just one of many types of herpes viruses that affect humans.
    - cjbgkagh 5y ago
      Oops, I thought the 90% was referring to HPV.
- Metacelsus 5y ago
  Neonatal HSV1, spread by unsanitary circumcisions, is a known problem in Orthodox Jewish communities.
ATsch 5y ago
blix 5y ago
I'm not sure hunting down viruses that don't cause problems in 90% percent of people is a good idea. Maybe they have some positive effect that we haven't realized yet. We are only just now catching up to the idea that bacteria are not always dangerous. There are probably other things we don't know. The tonsils and appendix recently were recategorized from vestigial organs to immune privileged bacteria resevoirs which play significant roles in the immune system. I think it would be a better idea to try to identify the reasons that some people have adverse reactions and some don't before going into the body and removing things.
- yaacov 5y ago
  It’s getting clearer and clearer that these viruses are extremely bad, see for example https://denovo.substack.com/p/epstein-barr-virus-more-maladies https://denovo.substack.com/p/epstein-barr-virus-more-maladi...
  - blix 5y ago
    EBV is linked to many, many things. But why does it only have these effects in some people and not others? Why is the prevalance of weird EBV-linked conditions increasing with time? Until these question are answered I don't think it's possible to call it uniquely bad.
    - ck2 5y ago
      EBV is typically activated by other stress. Hence "not a problem" for younger, healthier people. Until something unpredictable happens, like covid. One kind of long-covid is activated EBV by covid (there are other kinds). VZV (typo in my earlier post) hides in nerve cells waiting for immune weakness to attack (ie. shingles) Wildly high number of people have it dormant.
      - rkk3 5y ago
        Appendicitis is activated by inflammation and "not a problem" for most people. The Appendix organ hides in the body and waits to become inflamed to attack. It's certainly in the realm of possibility EBV or other viruses have no benefit, but the history of medicine is harmful medical intervention after harmful medical intervention...

by ck2 5y ago

okokwhatever 5y ago

Life and dead happens and whatever we try to fix about it will be a pursue of decades/centuries to achive. We're simply more aware about our humanity this days and we're more awaken about how simple is to suffer a terminal illness just "existing" not only smoking, eating fat or living an unhealthy life. I hope everyone learns about how life and dead works for the human being and not just trying to forget it submerging in an unreal dystopy of pills and pilates classes.

mrkramer 5y ago
>Life and dead happens Life is like Schrödinger's cat; you can be alive or dead at any moment it's all probability.
pengaru 5y ago
> smoking, eating fat or living an unhealthy life Eating fat is not unhealthy.
- nix23 5y ago
  >Eating fat is not unhealthy. True, let's correct it...sugar.
luckman212 5y ago
Interested to hear more about those dystopian pilates classes. And to think, I was shelling out my hard-earned money when I could have just been popping pills for the same effect.

pessimizer 5y ago

> Now HIV rising up "for decades"

mistrial9 5y ago

> 90% of people no, that varies by communities of people, defined by a graph of their location, hygiene and intimate practices. I can say that a different percentage probability applies to the graph of Orthodox Hasidim in Brooklyn versus the graph of professional basketball players in the USA.

cjbgkagh 5y ago
I always thought negatives was people who either haven’t had sex yet or haven’t had sex outside a closed loop. I’d be interested to see percentage effected normalized by number of partners. (Not interested enough to look it up now though)
- vsef 5y ago
  The viruses listed by parent aren't spread sexually, though they are all herpes viruses. EBV is also known as HSV-4 and gets to 60% plus prevalence in children, 90% in US adults. If there are populations with especially low prevalence I'm not aware of it. HSV-1 which causes mouth cold sores is present in 50-80% of people, also easily acquired in childhood. Only 20-40% of infected people get cold sores so most infected people don't realize they have it. Chicken pox/shingles is also a type of herpes virus with well known massive prevalence! Genital herpes is just one of many types of herpes viruses that affect humans.
  - cjbgkagh 5y ago
    Oops, I thought the 90% was referring to HPV.
Metacelsus 5y ago
Neonatal HSV1, spread by unsanitary circumcisions, is a known problem in Orthodox Jewish communities.

ATsch 5y ago

blix 5y ago

I'm not sure hunting down viruses that don't cause problems in 90% percent of people is a good idea. Maybe they have some positive effect that we haven't realized yet. We are only just now catching up to the idea that bacteria are not always dangerous. There are probably other things we don't know. The tonsils and appendix recently were recategorized from vestigial organs to immune privileged bacteria resevoirs which play significant roles in the immune system. I think it would be a better idea to try to identify the reasons that some people have adverse reactions and some don't before going into the body and removing things.

yaacov 5y ago
It’s getting clearer and clearer that these viruses are extremely bad, see for example https://denovo.substack.com/p/epstein-barr-virus-more-maladies https://denovo.substack.com/p/epstein-barr-virus-more-maladi...
- blix 5y ago
  EBV is linked to many, many things. But why does it only have these effects in some people and not others? Why is the prevalance of weird EBV-linked conditions increasing with time? Until these question are answered I don't think it's possible to call it uniquely bad.
  - ck2 5y ago
    EBV is typically activated by other stress. Hence "not a problem" for younger, healthier people. Until something unpredictable happens, like covid. One kind of long-covid is activated EBV by covid (there are other kinds). VZV (typo in my earlier post) hides in nerve cells waiting for immune weakness to attack (ie. shingles) Wildly high number of people have it dormant.
    - rkk3 5y ago
      Appendicitis is activated by inflammation and "not a problem" for most people. The Appendix organ hides in the body and waits to become inflamed to attack. It's certainly in the realm of possibility EBV or other viruses have no benefit, but the history of medicine is harmful medical intervention after harmful medical intervention...