It all comes down to what surface receptors the cancer is presenting on whether you can get T cells to attack it. If the B-specific receptors are gone on your

It all comes down to what surface receptors the cancer is presenting on whether you can get T cells to attack it. If the B-specific receptors are gone on your B-cell lymphoma, there may not be a great target left that isn't also on a bunch of cells you need. Each thing you do that targets "weird" characteristics of cancer (or bacterial infection, or pests) selects for cancer (or bacteria, or pests) that is presenting as less weird relative to everything else around.