3 ms·
I think you underestimate the effort needed to create an immunogenic vaccine candidate that doesn’t have unwanted side effects. That’s one of the reasons CureVa
by f6v 5y ago
I think you underestimate the effort needed to create an immunogenic vaccine candidate that doesn’t have unwanted side effects. That’s one of the reasons CureVac failed: https://www.nature.com/articles/d41586-021-01661-0 https://www.nature.com/articles/d41586-021-01661-0
And yes, AlphaFold is a major milestone, but I don’t think we’ve solved protein folding for good.
- et2o 5y agoCureVac did not have any pseudouridine modifications. This is relatively easy to do and I’m not sure why they did not do it.