Depends on your PDF and your goals, I think. JBIG2 is for raster data, but Matplotlib outputs vector images by default when producing PDFs. Rasterising may he

Depends on your PDF and your goals, I think. JBIG2 is for raster data, but Matplotlib outputs vector images by default when producing PDFs. Rasterising may help with things like huge numbers of points that hide each other, but at the cost of sharpness and scalability.