> high-risk low-incidence diseases like this conducted If you're asking 'how do we test the vaccine without _trying_ to give people HIV", one option is to giv

> high-risk low-incidence diseases like this conducted If you're asking 'how do we test the vaccine without _trying_ to give people HIV", one option is to give it to a lot of people, and record their outcomes over time. But first you need to prove the vaccine isnt like, super toxic in humans. So you do animal analog tests, then a limited test on humans, aka "Phase 1 trials". A previous article summarizes: > Moderna’s vaccines passed Phase I testing earlier this year, which involves testing for safety using only a handful of human volunteers. Phase II tests for a vaccine’s overall effectiveness, and with the move into Phase III, Moderna will be looking at its efficacy versus other prevention treatments currently on the market, such as pre-exposure prophylaxis, also known as PreP. - https://www.them.us/story/moderna-begins-hiv-vaccine-trials-covid-19-research https://www.them.us/story/moderna-begins-hiv-vaccine-trials-...