2 ms·

Could a large sample of phages be administered instead?

• chasil 5y ago
  The article discusses "training" phases, where the stock phage is applied to a sample of the specific pathogen, and only the most successful daughter phages are retained, over several repetitions. This process of encouraging adaptation appears to greatly increase successful outcomes.
  • sudosysgen 5y ago
    That makes sense for resistant infections, but for general infections a pre-made stock should work, no?
    • chasil 5y ago
      For something that is already resistant to antibiotics, the training phase seems prudent. Exploiting evolution as part of the treatment leads to greater success. The emergence of phage-resistant pathogens should not be encouraged, as we have encouraged antibiotic resistance. I think it's a change in mindset, as well as a change in procedure.