I advocate learning ASM to understand the machine; C and python are the same relation one step of abstraction up. So yes, more knowledge of C and how Python is

I advocate learning ASM to understand the machine; C and python are the same relation one step of abstraction up. So yes, more knowledge of C and how Python is written and what the interpreter is doing with your code is very likely to be helpful. Interfacing with python with your own C code is easy and the combination of the two is a much more powerful tool than either alone.