I would like to take time to debunk that whole article, but let's just focus on the article [1] I shared and to debunk his argumentation for the preprint articl

I would like to take time to debunk that whole article, but let's just focus on the article [1] I shared and to debunk his argumentation for the preprint article [2]. To begin with, you have to understand that the vitamin D3 supplement we take is usually cholecalciferol, which is metabolised by our body over a period of weeks into calcifediol. The key takeaway is that the usual supplement takes weeks to be effective. The RCT in article [1] is so strong because it supplements calcifediol at hospital intake, meaning the supplementation is immediately effective. So you can see that as a proxy for having supplemented with normal vitamin D for a couple of weeks prior. In article [2], the one he is promoting, cholecalciferol (normal vitamin D) is supplemented. This means it is unlikely that it will have a significant effect during the first weeks of admission. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456194/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456194/ [2] https://www.medrxiv.org/content/10.1101/2020.11.16.20232397v1 https://www.medrxiv.org/content/10.1101/2020.11.16.20232397v...