Looking at how current pandemic started from making of a hybrid of the SARS and an ACE2 using virus back in 2013 and that work's continuation in Wuhan, i'd say

Looking at how current pandemic started from making of a hybrid of the SARS and an ACE2 using virus back in 2013 and that work's continuation in Wuhan, i'd say that that is the money quote here: "Our study demonstrates the first case of ACE2 usage in MERS-related viruses, shedding light on a potential bio-safety threat of the human emergence of an ACE2 using 'MERS-CoV-2' with both high fatality and transmission rate."