4 ms·
If I remember it overloads the uptake of the methanol or something along those lines. Crazy stuff.
by shmoe 5y ago
If I remember it overloads the uptake of the methanol or something along those lines. Crazy stuff.
- andai 5y agoVery interesting. It's not the methanol that's toxic but its metabolites, so the ethanol slows down the liver's metabolism of methanol, stretching it out to the degree that the metabolites do not reach an unsafe concentration? Also, "The preferred antidote is fomepizole, with ethanol used if this is not available." https://en.wikipedia.org/wiki/Methanol_toxicity#Treatment https://en.wikipedia.org/wiki/Methanol_toxicity#Treatment >Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase, found in the liver. This enzyme plays a key role in the metabolism of ethylene glycol, and of methanol. https://en.wikipedia.org/wiki/Fomepizole https://en.wikipedia.org/wiki/Fomepizole