3 ms·
> I forget what it's called, but there's this phenomenon in immunology where the immune system can get "stuck" with whatever initial antibodies it comes up with
by ralph84 5y ago
> I forget what it's called, but there's this phenomenon in immunology where the immune system can get "stuck" with whatever initial antibodies it comes up with and doesn't adapt well.
It's called original antigenic sin[0]. It's one of the reasons that mass vaccination against a variant that is no longer circulating may not be the wisest strategy. But anyone who dares mention it is shouted down as anti-vaxx.
[0]https://en.wikipedia.org/wiki/Original_antigenic_sin https://en.wikipedia.org/wiki/Original_antigenic_sin
- xadhominemx 5y agoI guess that’s a theoretical possibility for a different virus, but in truth the mRNA vaccines provide robust protection from serious illness from omicron: https://ourworldindata.org/covid-deaths-by-vaccination https://ourworldindata.org/covid-deaths-by-vaccination
- s1artibartfast 5y agoIt is a possibility for any virus
- xadhominemx 5y agoWell it’s empirically not the case for Omicron, as the vaccines have continued to provide robust protection against hospitalization and death
- s1artibartfast 5y agoNeither the post you replied to or I said it applied to omicron. in fact, the parent said that it didn't. The fact that it didnt apply to omnicron, does not mean that it couldn't apply to covid, which is the claim you made.
- xadhominemx 5y agoSo it’s about a theoretical future variant?
- s1artibartfast 5y agoThe point was that it could have happened with Covid-19, and could still happen with Covid-19. Probably not very likely, but to say Covid-19 is somehow outside the scope of original antigenic sin theory is silly.
- xadhominemx 5y agoOk, not sure what point you’re trying to make then. The vaccines worked very well against delta and omicron variants and had we halted vaccinations once variants began to take hold it would have cost millions of lives. There are many thousands of known variants of Covid-19
- s1artibartfast 5y agoMy only point was to provide correction to your erroneous statement. >I guess that’s a theoretical possibility for a different virus Im not trying to claim it applied to omicron, current vaccine efficacy, that we should halt vaccinations, or any other strawman you are trying to put up. You can simply acknowledge the correction