Of related interest is my Typesetting Markdown series (skip to the later parts to see R and annotations): https://dave.autonoma.ca/blog/2019/05/22/typesetting-

Of related interest is my Typesetting Markdown series (skip to the later parts to see R and annotations): https://dave.autonoma.ca/blog/2019/05/22/typesetting-markdown-part-1/ https://dave.autonoma.ca/blog/2019/05/22/typesetting-markdow... I've been working on an editor that can interpolate string variables to replace those scripts: https://github.com/DaveJarvis/keenwrite/blob/master/docs/screenshots.md https://github.com/DaveJarvis/keenwrite/blob/master/docs/scr... Many Markdown publishing systems put YAML headers into Markdown documents, which feels like mixing presentation with content. With KeenWrite you can do: keenwrite -i filename.Rmd -o filename.pdf -v variables.yaml Meaning, if you wanted to apply a different set of values, you can supply a different file, without having to modify the R Markdown source. (Of course, you can always write shell scripts to concatenate the YAML header prior to processing.)