3 ms·
The impact that AlphaFold is already having on speeding up drug discovery
- was_a_dev 5y agoWhat is the licensing of AlphaFold? If the drug makes it to market, does the creators owe royalties?
- eesmith 5y agoOne of the follow-ups points to https://github.com/deepmind/alphafold/issues/14#issuecomment-1016728634 https://github.com/deepmind/alphafold/issues/14#issuecomment... which comments "Hi, we have recently changed the license terms for the AlphaFold weights to CC BY 4.0, which permits commercial use", from 4 days ago. It looks like the source license at https://github.com/deepmind/alphafold/blob/main/LICENSE https://github.com/deepmind/alphafold/blob/main/LICENSE is Apache 2.0.
- was_a_dev 5y agoSounds like that startup was hedging their bets for the license to change
- samaman 5y agoI'd be very very worried about a protein model that just came out alphafold to be used to come up with drug targets without at least some molecular dynamics simulation of the solution within which that protein works with. There may be other glycans, ligands, or wholly different metabollites that could affect this binding.