3 ms·
Makes me wonder if this was discovered in mice engineered for inducible gene expression. TET/doxy mice are commonly used in experiments where you want to sele
by subroutine 5y ago
Makes me wonder if this was discovered in mice engineered for inducible gene expression. TET/doxy mice are commonly used in experiments where you want to selectively turn on or off a particular gene.
https://pubmed.ncbi.nlm.nih.gov/27216914/ https://pubmed.ncbi.nlm.nih.gov/27216914/
- flobosg 5y agoI might be wrong, but I think that TET enzymes and the Tet-Off/Tet-On system are not related.
- Retr0 5y agoYeah TET here is ten-eleven translocation (https://en.wikipedia.org/wiki/TET_enzymes https://en.wikipedia.org/wiki/TET_enzymes), not tetracycline (https://en.wikipedia.org/wiki/Tetracycline-controlled_transcriptional_activation https://en.wikipedia.org/wiki/Tetracycline-controlled_transc...).