I hope this gets investigated further, the proposed mechanism is actually pretty interesting My interpretation is that the primary mechanism can be summed up t

I hope this gets investigated further, the proposed mechanism is actually pretty interesting My interpretation is that the primary mechanism can be summed up to a modulatory effect lowering the activation threshold on the IRE1α and interferon pathways for breakdown of viral RNA I'd like to understand if/how/where CBD may actually be binding/interacting to modulate these pathways The authors also bring up the issue of CBD forming large micelles and being captured by the liver limiting the amount distributed to other tissues. I'm unsure if the formation of micelles is the issue at hand here, but there are cannabinoids products available while have been sonicated and sprayed into small particles with a surfactant to make them water soluble. This could be an interesting delivery method to achieve greater tissue distribution. I'm not sure how much its been studied (if at all) but my personal anecdote with these products is that they do achieve a high blood plasma concentration very rapidly compared to "normal" edibles in a fatty carrier.