3 ms·Prions survive autoclave, meat has to be charred inside out for prions to die. It's nightmare fuel.by ysleepy 5y agoPrions survive autoclave, meat has to be charred inside out for prions to die. It's nightmare fuel.chmod775 5y agoOh well. Looks like you need about 500C for several houses to reliably denature them.chmod775 5y ago*hours