I agree that it seems at least plausible that a cure will be found in the future. The cell already has a number of quality control mechanisms for detecting misf

I agree that it seems at least plausible that a cure will be found in the future. The cell already has a number of quality control mechanisms for detecting misfolded proteins. It seems not unusual that we'd be able to piggyback onto this system do develop something that can detect specific prions and neutralize or destroy them, possibly delivered an an RNA shot. The problem is that there are a minuscule number of prion deaths in the developed world, so I don't see it getting a huge amount of attention. On the other hand, the Covid RNA vaccines were basically invented by a handful of people looking at a string of nucleotides over the course of five days. (It took large companies to actually develop the vaccine itself, of course.) This could end up being something that's solved by more accurate protein-folding simulations (perhaps Google's AlphaFold) and a couple of grad students.