I also forgot to mention serendipity, which in my experience is critical to innovation. For me, working remotely drastically reduces serendipitous interactions.

I also forgot to mention serendipity, which in my experience is critical to innovation. For me, working remotely drastically reduces serendipitous interactions. And I say this as an introvert who loves to be left alone for long stretches to do focused work. (note, my experience is mostly in academia, but with 4 years of commercial experience out of 24 years total.)