3 ms·

I think that finding a cancerous liver cell in your neck means metastasis is happening, and the slow process is assumed to be complete. Unless the immune system

by chasil 5y ago

I think that finding a cancerous liver cell in your neck means metastasis is happening, and the slow process is assumed to be complete. Unless the immune system is attacking these cells and their numbers are controlled, this would be stage 4 (while I am not a physician, let alone an oncologist). I think that the best weapon that the general public has against cancer is autophagy, triggered by keeping blood glucose very low at least some of the time. Metabolic changes that can awaken apoptosis might kill many of these mutation carriers.

vmception 5y ago
> I think that finding a cancerous liver cell in your neck means metastasis is happening, and the slow process is assumed to be complete. To me thats what I said, that's what stage 4 means, metastasized. > I think that the best weapon that the general public has against cancer is autophagy One can wish
- TedDoesntTalk 5y ago
  > One can wish It's not really a wish anymore. There are studies showing this, but I'm too busy to find them for you. Rhonda Patrick at https://www.foundmyfitness.com/ https://www.foundmyfitness.com/ has interviews with various researchers on this topic. Here are some, but this is by no means exhaustive: https://www.foundmyfitness.com/episodes/autophagy-and-cancer-a-crucial-role-in-immunosurveillance-and-chemotherapeutic-treatment https://www.foundmyfitness.com/episodes/autophagy-and-cancer... https://www.foundmyfitness.com/episodes/cancer-manipulates-systems-autophagy https://www.foundmyfitness.com/episodes/cancer-manipulates-s... https://www.foundmyfitness.com/episodes/caloric-restriction-mimetics-in-aging-improved-cancer-chemotherapy-autophagy-anti-obesity-effect https://www.foundmyfitness.com/episodes/caloric-restriction-... My layman understanding is that healthy cells can withstand the rigors of fasting and fasting-mimicking, but many cancer cells cannot. They die.
Jimmc414 5y ago
>I think that the best weapon that the general public has against cancer is autophagy, triggered by keeping blood glucose very low at least some of the time. Metabolic changes that can awaken apoptosis might kill many of these mutation carriers. Since fasting is the best way to induce autophagy, that could explain the apparent negative correlation between cancer rate and a country's food supply [.] http://globalcancermap.com/ http://globalcancermap.com/ [.] https://ourworldindata.org/food-supply https://ourworldindata.org/food-supply
- vmception 5y ago
  no, thats explained at how young people die, also related to a country’s food and water supply Africa’s average age is half of North America’s, and after controlling for infant mortality still so few other people make it to the much higher life expectancy limit (which is still 10-15 years lower than North America) there that there isnt opportunity for cancer diagnosis to rear up as often! Let alone be tested for cancer to understand if that was an ailment or contributing comorbidity.
  - appletrotter 5y ago
    Makes sense, but can you prove it?
    - vmception 5y ago
      which parts? you really want me to provide sources on average age as well as life expectancy? you don't know the accepted consensuses on why societies in the continent of Africa operate in abysmal conditions to support human life uninterrupted? I don't think I'm compelled to provide that but I'm open to counter theories
      - appletrotter 5y ago
        The counter theory is the comment that OP made. Your response opens with a denial of OPs theory; this response would be more effective with citations. Your theory makes sense, but I just don't see why it has to be mutually exclusive. Maybe they're both factors to varying degrees?
        vmception 5y ago
        sure, I can accept a multipronged explanation, I already acknowledged that both of our observations are related to the food supply issues chronic on that continent, I don't think their specific correlation has been studied though so there's nothing to really say. My hypothesis is that my observations (which have been studied and are actively being addressed by many organizations) are going to have a greater weight by mere deduction: there is nothing unique enough about people in Africa that would make cancer appear earlier, and since they die earlier there and have worse preventative treatment to know other upcoming ailments, the cancer wouldn't come up because they're already dead from other basic infrastructure issues. What I'm reading is "hey here is this ailment people get in their 60s, here's this continent where people barely survive until their 60s, do you have a citation for why people there don't frequently get that ailment there? we should really study that"
rsync 5y ago
"I think that the best weapon that the general public has against cancer is autophagy" It would be but it's so, so, ever so hard, to go without even one single meal. I've stopped evangelizing "fasting" or even shorter intake windows. If you can't be bothered to skip breakfast for a few weeks just to see how your body responds then let's stop wasting our time and just talk about football or something. ... how 'bout them Cowboys ?!
- coldtea 5y ago
  >It would be but it's so, so, ever so hard, to go without even one single meal. Huh? You'd be surprised...
  - sersi 5y ago
    I think it really depends on people, I've never had issues skipping breakfast and lunch. When I'm busy enough I will forget to eat easily. But I know a lot of people who cannot skip a single meal and get irritated or angry.
    - coldtea 5y ago
      >But I know a lot of people who cannot skip a single meal and get irritated or angry. I think they just need to get used to some poverty for a while.
    - tremon 5y ago
      True, but I'd posit that the irritation and anger are effectively withdrawal symptoms; eating to avoid those symptoms is similar to keep lighting cigarettes because your hands tremble when you go without. (Of course, it's not that black&white, and not eating at all will quickly deteriorate your health -- I'm just saying that hangriness is not the same as hunger, and learning to differentiate between the two is important)
    - deleted 5y ago
      [deleted]

by chasil 5y ago

vmception 5y ago

> I think that finding a cancerous liver cell in your neck means metastasis is happening, and the slow process is assumed to be complete. To me thats what I said, that's what stage 4 means, metastasized. > I think that the best weapon that the general public has against cancer is autophagy One can wish

TedDoesntTalk 5y ago
> One can wish It's not really a wish anymore. There are studies showing this, but I'm too busy to find them for you. Rhonda Patrick at https://www.foundmyfitness.com/ https://www.foundmyfitness.com/ has interviews with various researchers on this topic. Here are some, but this is by no means exhaustive: https://www.foundmyfitness.com/episodes/autophagy-and-cancer-a-crucial-role-in-immunosurveillance-and-chemotherapeutic-treatment https://www.foundmyfitness.com/episodes/autophagy-and-cancer... https://www.foundmyfitness.com/episodes/cancer-manipulates-systems-autophagy https://www.foundmyfitness.com/episodes/cancer-manipulates-s... https://www.foundmyfitness.com/episodes/caloric-restriction-mimetics-in-aging-improved-cancer-chemotherapy-autophagy-anti-obesity-effect https://www.foundmyfitness.com/episodes/caloric-restriction-... My layman understanding is that healthy cells can withstand the rigors of fasting and fasting-mimicking, but many cancer cells cannot. They die.

Jimmc414 5y ago

>I think that the best weapon that the general public has against cancer is autophagy, triggered by keeping blood glucose very low at least some of the time. Metabolic changes that can awaken apoptosis might kill many of these mutation carriers. Since fasting is the best way to induce autophagy, that could explain the apparent negative correlation between cancer rate and a country's food supply [.] http://globalcancermap.com/ http://globalcancermap.com/ [.] https://ourworldindata.org/food-supply https://ourworldindata.org/food-supply

vmception 5y ago
no, thats explained at how young people die, also related to a country’s food and water supply Africa’s average age is half of North America’s, and after controlling for infant mortality still so few other people make it to the much higher life expectancy limit (which is still 10-15 years lower than North America) there that there isnt opportunity for cancer diagnosis to rear up as often! Let alone be tested for cancer to understand if that was an ailment or contributing comorbidity.
- appletrotter 5y ago
  Makes sense, but can you prove it?
  - vmception 5y ago
    which parts? you really want me to provide sources on average age as well as life expectancy? you don't know the accepted consensuses on why societies in the continent of Africa operate in abysmal conditions to support human life uninterrupted? I don't think I'm compelled to provide that but I'm open to counter theories
    - appletrotter 5y ago
      The counter theory is the comment that OP made. Your response opens with a denial of OPs theory; this response would be more effective with citations. Your theory makes sense, but I just don't see why it has to be mutually exclusive. Maybe they're both factors to varying degrees?
      - vmception 5y ago
        sure, I can accept a multipronged explanation, I already acknowledged that both of our observations are related to the food supply issues chronic on that continent, I don't think their specific correlation has been studied though so there's nothing to really say. My hypothesis is that my observations (which have been studied and are actively being addressed by many organizations) are going to have a greater weight by mere deduction: there is nothing unique enough about people in Africa that would make cancer appear earlier, and since they die earlier there and have worse preventative treatment to know other upcoming ailments, the cancer wouldn't come up because they're already dead from other basic infrastructure issues. What I'm reading is "hey here is this ailment people get in their 60s, here's this continent where people barely survive until their 60s, do you have a citation for why people there don't frequently get that ailment there? we should really study that"

rsync 5y ago

"I think that the best weapon that the general public has against cancer is autophagy" It would be but it's so, so, ever so hard, to go without even one single meal. I've stopped evangelizing "fasting" or even shorter intake windows. If you can't be bothered to skip breakfast for a few weeks just to see how your body responds then let's stop wasting our time and just talk about football or something. ... how 'bout them Cowboys ?!

coldtea 5y ago
>It would be but it's so, so, ever so hard, to go without even one single meal. Huh? You'd be surprised...
- sersi 5y ago
  I think it really depends on people, I've never had issues skipping breakfast and lunch. When I'm busy enough I will forget to eat easily. But I know a lot of people who cannot skip a single meal and get irritated or angry.
  - coldtea 5y ago
    >But I know a lot of people who cannot skip a single meal and get irritated or angry. I think they just need to get used to some poverty for a while.
  - tremon 5y ago
    True, but I'd posit that the irritation and anger are effectively withdrawal symptoms; eating to avoid those symptoms is similar to keep lighting cigarettes because your hands tremble when you go without. (Of course, it's not that black&white, and not eating at all will quickly deteriorate your health -- I'm just saying that hangriness is not the same as hunger, and learning to differentiate between the two is important)
  - deleted 5y ago
    [deleted]